Dr. Reese’s Bits and Pieces
June 2017 Newsletter
Hard to believe I’m writing the June newsletter as the snow is piling up outside! Good old Colorado weather…
Endocrine System Part 3
The last two months (April and May newsletters are posted on the website) I’ve been talking about the endocrine system and the main concerns that must be addressed to help balance someone’s hormones:
There are 4 main areas that must be addressed to balance someone’s endocrine system:
I covered in detail blood sugar imbalance and insulin surges plus the problems they cause.
Essential Fatty Acids
Many of us grew up in a fat-phobic world were all fats were bad. It’s true that trans fats are bad but in moderation the rest of the fats are good. Essential means that they must be in your diet since your body can’t make them. Omega 3 and 6 are the essential fatty acids that you need to eat or supplement to stay healthy and to produce prostaglandins which are necessary for proper hormone signaling. Prostaglandins affect multiple hormone synthesis and secretion pathways in the hypothalamus-pituitary axis as well as ovulation, implantation and menstruation. Omega 3 are vital for fertility problems.
Omega 6 can produce prostaglandin 1 (PG-1) and 2 (PG-2) while omega-3 produces PG-3. PG-1 and 3 are anti-inflammatory and prevent clotting. PG-2 creates inflammation, swelling and clotting. A balance between PG-1,3 and PG-2 is vital for healthy function and ideal hormone signaling. Increased consumption of omega 6 fatty acids in the diet from fried foods and vegetable oils, shifts the away from PG-1 into PG-2 production.
The Standard American Diet (SAD) is high in omega-6 and low in omega-3 creating a shift into inflammatory prostaglandin production. Excess sugar, trans fats, insulin surges, inflammation, protein deficiencies, hypothyroid and alcohol consumption can affect which PG’s are made. Finally, a deficiency in vitamins B3, B6, magnesium, zinc and molybdenum can affect PG production. Natural hormone replacement is not going to fix a fatty acid imbalance or insulin surges.
Normalize Gut Function and Flora
Here are some key points about the human body's microbial population:
Dysbiosis is and over-growth of abnormal microbes such as certain bacteria, yeast, parasites, etc., that do not have a beneficial role in microbiota. One of the best sources of good bacteria is to eat fermented foods. Vinegar, olives, pickles, sauerkraut, kim chi, etc. I am not a fan of kombucha since it rarely tests well on patients.
Microbiome dysbiosis disrupts intestinal breakdown of hormones and reduces hormonal clearance and causes hormone dysregulation. It also reduces the metabolic effect from natural supplements.
Leaky gut is a breakdown of the intestinal barrier that allows large proteins, microbes and toxins to sneak into the systemic circulation. It is caused by numerous factors:
You can see why leaky gut is so prevalent and needs to be treated before you can be healthy.
With a leaky gut, Lipopolysaccharides (LPS) slips through the breaks in the intestinal barrier and into the blood.
This creates dysregulation of the hypothamic-pituitary axis which alters estrogen, testosterone and progesterone feedback.
LPS alters cortisol responses and creates adrenal fatigue. LPS creates systemic inflammation which promotes insulin resistance, downregulation of hormone enzyme pathways and promotes hormone shifts.