Dr. Reese’s Bits and Pieces
June 2019 Newsletter
I know the weather this week doesn’t feel very summer-like, but I do think summer will arrive this month as planned. All this rain has been hard on my golf game, but really, even sunny days don’t help it get better. I still enjoy playing and that’s what matters! We all need to find a physical activity we enjoy and do it on a regular basis to keep us healthy.
In May, I attended two different weekend seminars and they both were passing along the latest research about how if your gut is on fire, your brain is on fire. It is an epidemic in this country and part of the reason why dementia and Alzheimer’s are on the rise.
Every system in the body is controlled by and sends information to your brain. What protects the brain arethe hard bones of the skull and the blood brain barrier (BBB). Your gut and lungs also have barriers to protect them from the poisons of the outside world. If the gut and/or lung barriers break down, then all kinds of infections, toxins, poisons, large protein molecules, etc. get into the blood. Usually, if you have a leaky gut, you will also have a leaky brain and vice versa. One test for leaky brain is to ingest 1000 mg of GABA and see if you have a calmingreaction to it. If you do, you have a leaky brain since GABA is too large to cross an intact BBB.
Neuroinflammation is the result of many different triggers that can start your brain on fire:
Lack of Sleep Dietary ProteinReactivity Infections
Chemical Triggers InflammatoryDisease Inflammatory Diet
OvertrainingSyndrome PsychologicalTriggers Impacts to the head
You can see how lifestyle choices can create a real problem for our poor brains. Eating foods that you know your body is reactive to doesn’t just affect your stomach or digestion. It also attacks your brain. Dietary protein examples are gluten, casein, whey, etc.
Many people look at food reactions like alcohol. If I drink too much today, I’ll feel bad tomorrow but the next day I’ll be fine. Not so with foods your body has tested to be reactive to. That inflammation can go on for months. Gluten ataxia is a destruction of the cerebellum caused by gluten antibodies attacking it and permanently changing the way you walk.Alcohol is considered a chemical trigger. Cheers!
These are the cells that make up 90% of your brain. They get turned on by the triggers above and unfortunately are hard to turn off. The inflammatory response from the above triggers permanently changes the structure of the glial cells and they are forever sensitized to any future triggers. How do you know if have brain on fire?
• Brain fog
• Inability to focus or concentrate
• Poor memory or recall
• Inability to handle stimulation (crowed environments, loud noises, etc.)
• A need for excessive sleep
• Poor endurance with brain activities
• Chronic Fatigue Syndrome
• Post-Traumatic Stress Syndrome
• Post-Concussion Syndrome
• Chronic Pain Syndrome
• Neurodegenerative Disease (Dementia #1, Parkinson’s #2)
CLINICAL MANAGEMENT OF NEUROINFLAMMATION
LEVEL 1 • Lifestyle • Diet • Anti-Inflammatory Nutraceuticals:
These are things you can do for yourself to help reduce neuroinflammation. Get 7-9 hours of sleep, eat a non-inflammatory diet, reduce stress (possible job-ectomy or ending toxic relationships), high intensity exercise of short duration and alcohol avoidance are lifestyle and dietfixes.
Nutraceuticals: Polyphenols-Resveratrol (Liposomal), Curcumin (Liposomal), Apigenin, Luteolin, Baicalein,Rutin.
Essential Fatty Acids-EPA/DHA. Short-Chain Fatty Acids-Butyrate Acetate, Propionate.
Nutrients- Magnesium. Antioxidants-Glutathione, Polyphenols.
For marijuana users, good pure CBD’s help reduce inflammation, but THC increases brain inflammation so beware.
LEVEL 2 Systems Biology Approach:
Blood-Brain Barrier Permeability, Infection, Hormone Imbalances, Environmental Toxins, Hypoxia Immune Dysregulation Oxidative Stress. These things we can help you with and figure out what you need to reduce neuroinflammation.